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Ras/Raf/MAPK signaling has been highlighted as an important contributor to the pathology of Keratosis Pilaris
Funding: This work was supported by a NIH grant AI 15122 ( The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
Specifically, among the effects triggered by increased ROS in the lens related to cataract development are the oxidation and induction of crystalline aggregation, leading to lens opacity and DNA damage resulting in mutations
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